Alveolar bone changes due to excessive occlusal stress.

Effects of occlusal loading on alveolar bone remodeling and changes in the distribution of neuropeptides after tooth replantation in rats.

Biomechanical and biochemical factors are involved in bone remodeling. Occlusal loading is a well-known mechanical modulator of alveolar bone remodeling. Neuropeptides, such as vasoactive intestinal peptide (VIP) and calcitonin generelated peptide (CGRP), have been described within the biochemical bone regulators. In this study, the influences of occlusal loading on the alveolar bone remodeling...

Cutis laxa and excessive bone growth due to de novo mutations in PTDSS1

The cutis laxa syndromes are multisystem disorders that share loose redundant inelastic and wrinkled skin as a common hallmark clinical feature. The underlying molecular defects are heterogeneous and 13 different genes have been involved until now, all of them being implicated in elastic fiber assembly. We provide here molecular and clinical characterization of three unrelated patients with a v...

Occlusal Disorders among Patients with Total Clefts of Lip, Alveolar Bone, and Palate

Clefts are common birth defects. They are accompanied by various malformations, including disturbances in facial look as well as skeletal disorders that include malocclusions, most frequently crossbites and class III anomalies. The aim of the study was to present the commonest malocclusions in patients with total cleft of the lip, alveolar bone and palate (n = 154) and compare the results to th...

Myocardial antioxidant and oxidative stress changes due to sex hormones.

The purpose of the present study was to examine myocardial antioxidant and oxidative stress changes in male and female rats in the presence of physiological sex hormone concentrations and after castration. Twenty-four 9-week-old Wistar rats were divided into four groups of 6 animals each: 1) sham-operated females, 2) castrated females, 3) sham-operated males, and 4) castrated males. When testos...

Evidence Report: Risk of Bone Fracture due to Spaceflight- induced Changes to Bone